# Cynthia Smith > Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero. ## Record | Field | Value | | --- | --- | | Representation | alpha-profile-markdown-v4 | | Protocol | Alpha Governance Facts Protocol 0.1 | | Schema | alpha.governance.entity.public.v1 | | Record version | public-0:d751713988987e9331980363e24189ce | | Governance record representation | alpha-governance-record-v2 | | Canonical entity | alpha:person:cynthia-smith | | Entity type | Person | | Canonical URL | https://registry.alpha.ac/people/cynthia-smith | | Publication | PUBLISHED | | Verification | corroborated | | Verification schema | alpha-verification-states-v1 | | Ownership | unclaimed | | Published claims | 18 | | Claims under review | 0 | | Evidence records | 15 | | Conflicts | 0 | | Conflicts in internal review | 0 | | Observed | 2026-10-17T03:18:14.720931+00:00 | | Last reviewed | 2026-05-16T02:53:17.26+00:00 | ## Identity - Legal name: Cynthia Smith - Display name: Cynthia Smith ## Alpha Governance Record | Field | Value | | --- | --- | | Governance Record schema | alpha-governance-record-v2 | | Ontology | alpha-governance-ontology-v1 | | Record version | public-0:d751713988987e9331980363e24189ce | | As of | 2026-10-17T03:18:14.99854+00:00 | | Completeness | 1 | | Record Quality | 0.938 | | Directors | 0 | | Committees | 0 | | Governance events | 5 | | Entity class | person | ## Section coverage | Section | State | | --- | --- | | identity | PUBLISHED | | corporate_structure | NOT_APPLICABLE | | board | NOT_APPLICABLE | | committees | NOT_APPLICABLE | | leadership | NOT_APPLICABLE | | ownership | NOT_APPLICABLE | | financials | NOT_APPLICABLE | | capital_structure | NOT_APPLICABLE | | compensation | NOT_APPLICABLE | | governance | NOT_APPLICABLE | | shareholder_governance | NOT_APPLICABLE | | audit | NOT_APPLICABLE | | legal | NOT_APPLICABLE | | risk | NOT_APPLICABLE | | cyber | PUBLISHED | | ai_governance | PUBLISHED | | agent_governance | NOT_APPLICABLE | | markets_external | NOT_APPLICABLE | | events | PUBLISHED | | relationships | PUBLISHED | | assessments | PUBLISHED | | evidence | PUBLISHED | ## Governance events - DIRECTOR_APPOINTED: Cynthia Smith seat on Tvardi Therapeutics, Inc., effective 2025-01-01. Effective: 2025-01-01. Detected: 2026-05-16T02:53:17.26+00:00. event_id=alpha:event:transition:1fd35qi100nzyi - DIRECTOR_APPOINTED: Cynthia Smith seat on AGIOS PHARMACEUTICALS, INC., effective 2022-01-01. Effective: 2022-01-01. Detected: 2026-05-16T02:53:17.26+00:00. event_id=alpha:event:transition:xinds6tvllrk - DIRECTOR_APPOINTED: Cynthia Smith seat on Protara Therapeutics, Inc., effective 2021-01-01. Effective: 2021-01-01. Detected: 2026-05-16T02:53:17.26+00:00. event_id=alpha:event:transition:dsupa81rl28vk - DIRECTOR_APPOINTED: Cynthia Smith seat on Spero Therapeutics, Inc., effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-05-16T02:53:17.26+00:00. event_id=alpha:event:transition:achb8p1nlkxg1 - DIRECTOR_APPOINTED: Cynthia Smith seat on Akebia Therapeutics, Inc., effective 2018-01-01. Effective: 2018-01-01. Detected: 2026-05-16T02:53:17.26+00:00. event_id=alpha:event:transition:ubz02z1v1w329 ## Scoped resources - `alpha://person/cynthia-smith` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record - `alpha://person/cynthia-smith/identity` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=identity - `alpha://person/cynthia-smith/corporate-structure` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=corporate-structure - `alpha://person/cynthia-smith/board` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=board - `alpha://person/cynthia-smith/committees` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=committees - `alpha://person/cynthia-smith/leadership` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=leadership - `alpha://person/cynthia-smith/ownership` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=ownership - `alpha://person/cynthia-smith/financials` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=financials - `alpha://person/cynthia-smith/capital-structure` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=capital-structure - `alpha://person/cynthia-smith/compensation` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=compensation - `alpha://person/cynthia-smith/governance` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=governance - `alpha://person/cynthia-smith/shareholder-governance` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=shareholder-governance - `alpha://person/cynthia-smith/audit` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=audit - `alpha://person/cynthia-smith/legal` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=legal - `alpha://person/cynthia-smith/risk` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=risk - `alpha://person/cynthia-smith/cyber` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=cyber - `alpha://person/cynthia-smith/ai-governance` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=ai-governance - `alpha://person/cynthia-smith/agents` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=agents - `alpha://person/cynthia-smith/ecosystem` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=ecosystem - `alpha://person/cynthia-smith/events` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=events - `alpha://person/cynthia-smith/relationships` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=relationships - `alpha://person/cynthia-smith/assessments` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=assessments - `alpha://person/cynthia-smith/evidence` (contract): https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record§ion=evidence ## Role modules - Director ## Attention - NO_RECORDS_FOUND ## Committee data - NO_RECORDS_FOUND ## Leadership - PUBLISHED ## Roles - Director at Tvardi Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:role:1. Valid from: 2025-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6c81bfe4af0174d03292a7890551a9d8b90f766b9ece57720ea4aeed3c246003. - Director at AGIOS PHARMACEUTICALS, INC.. Claim: alpha:claim:person:cynthia-smith:role:2. Valid from: 2022-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:4c2b7df3c489fe8ccb13c9d1bdc1b217bbc1963de3a3b09d4b6f3bd6168093cf. - Director at Protara Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:role:3. Valid from: 2021-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:436b1d05cbd3cedd2e436645f41876bb99d84c3e889f2f05fcd47f38c1499d2d. - Director at Spero Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:role:4. Valid from: 2019-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c. - Director at Akebia Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:role:5. Valid from: 2018-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9377fc911c4ee4f4277341059f915d23a8392e952db25de5330d8a73afb329d9. ## Governance - PUBLISHED ## Board committees - PUBLISHED ## AI and ML experience - AI and ML experience: not identified in the cited filing. Claim: alpha:claim:person:cynthia-smith:ai_ml_experience:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205. ## Board membership - Serves on the board of AGIOS PHARMACEUTICALS, INC.. Claim: alpha:claim:person:cynthia-smith:board_membership:2. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:349feaafa56c296ebf6b934eb4adf6ba16ae6176f83e79582c977b4e75f62486. - Serves on the board of Akebia Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:board_membership:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:86261273562f67a01dba081b1ef5e65d436cae1d10d74d002b2970a6c40c68c2. - Serves on the board of Protara Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:board_membership:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:847fad036ba319aa19100716b06206bbe60c404b5d9c77c8bbf36dc621224545. - Serves on the board of Spero Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:board_membership:5. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71. - Serves on the board of Tvardi Therapeutics, Inc.. Claim: alpha:claim:person:cynthia-smith:board_membership:6. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:03e37199347a641e01211612cd6672100c83aa615de7c781e844abd2f2f078cf. ## Board role - Board role: Director. Claim: alpha:claim:person:cynthia-smith:board_role:7. Valid from: 2025-04-25. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:projection-evidence:document:8be51d1f9be1dfe6bca8f9ae35ea1e6f9a6e2ca2db2fa7ba5c9bf13448807c4d, alpha:projection-evidence:document:b18c4634bc858a39f6aac9d1fce708ab91c1e33b11a4654801a7369dd693a33d, alpha:projection-evidence:document:2cb572ec2d88499e8ad58ea8e8f271b262b5eccd3cb67a93c886bccbbb52e2c8, alpha:projection-evidence:document:67337eb7f33b2430c6b7698273d910fba75065348b4f5405669781a747ac78be, alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205. ## Committee assignments - No committee assignment disclosed in the cited filing. Claim: alpha:claim:person:cynthia-smith:committee_assignments:8. Valid from: 2025-04-25. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:67337eb7f33b2430c6b7698273d910fba75065348b4f5405669781a747ac78be. - Committee assignments: Compensation. Claim: alpha:claim:person:cynthia-smith:committee_assignments:9. Valid from: 2025-04-25. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:projection-evidence:document:2cb572ec2d88499e8ad58ea8e8f271b262b5eccd3cb67a93c886bccbbb52e2c8, alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205. - Committee assignments: Compensation, Research/Innovation. Claim: alpha:claim:person:cynthia-smith:committee_assignments:10. Valid from: 2025-04-29. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b18c4634bc858a39f6aac9d1fce708ab91c1e33b11a4654801a7369dd693a33d. - Committee assignments: Nominating/Governance. Claim: alpha:claim:person:cynthia-smith:committee_assignments:11. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:8be51d1f9be1dfe6bca8f9ae35ea1e6f9a6e2ca2db2fa7ba5c9bf13448807c4d. ## Cybersecurity experience - Cybersecurity experience: not identified in the cited filing. Claim: alpha:claim:person:cynthia-smith:cybersecurity_experience:12. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205. ## Technology background - Technology background: not identified in the cited filing. Claim: alpha:claim:person:cynthia-smith:technology_background:13. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205. ## Coverage states | Field | Value | | --- | --- | | Identity | PUBLISHED | | Business | NOT_APPLICABLE | | Leadership | PUBLISHED | | Board and committees | PUBLISHED | | Governance | PUBLISHED | | Financials | NOT_APPLICABLE | | Workforce | NOT_APPLICABLE | | Ownership | NOT_APPLICABLE | | Ratings | NOT_PUBLISHED | | Market and index context | NOT_APPLICABLE | ## Public sources - alpha:projection-evidence:document:8be51d1f9be1dfe6bca8f9ae35ea1e6f9a6e2ca2db2fa7ba5c9bf13448807c4d: [TVRD DEF 14A director slate](https://www.sec.gov/Archives/edgar/data/1346830/000110465926047695/tvrd-20260609xdef14a.htm). - alpha:projection-evidence:document:6c81bfe4af0174d03292a7890551a9d8b90f766b9ece57720ea4aeed3c246003: [sec_proxy](https://www.sec.gov/Archives/edgar/data/1346830/000110465926047695/tvrd-20260609xdef14a.htm). - alpha:projection-evidence:document:b18c4634bc858a39f6aac9d1fce708ab91c1e33b11a4654801a7369dd693a33d: [AKBA DEF 14A director slate](https://www.sec.gov/Archives/edgar/data/1517022/000151702225000023/akba-20250429.htm). - alpha:projection-evidence:document:9377fc911c4ee4f4277341059f915d23a8392e952db25de5330d8a73afb329d9: [sec_proxy](https://www.sec.gov/Archives/edgar/data/1517022/000151702225000023/akba-20250429.htm). - alpha:projection-evidence:document:2cb572ec2d88499e8ad58ea8e8f271b262b5eccd3cb67a93c886bccbbb52e2c8: [SPRO DEF 14A director slate](https://www.sec.gov/Archives/edgar/data/1701108/000119312525100544/d797305ddef14a.htm). - alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c: [sec_proxy](https://www.sec.gov/Archives/edgar/data/1701108/000119312525100544/d797305ddef14a.htm). - alpha:projection-evidence:document:30b2ff403057d089a831775d1a9288051be65316b642ded9415147ae44be9205: [TARA DEF 14A director slate](https://www.sec.gov/Archives/edgar/data/1359931/000121390025035568/ea0239092-01.htm). - alpha:projection-evidence:document:67337eb7f33b2430c6b7698273d910fba75065348b4f5405669781a747ac78be: [AGIO DEF 14A director slate](https://www.sec.gov/Archives/edgar/data/1439222/000119312525096719/d838751ddef14a.htm). - alpha:projection-evidence:document:4c2b7df3c489fe8ccb13c9d1bdc1b217bbc1963de3a3b09d4b6f3bd6168093cf: [sec_proxy](https://www.sec.gov/Archives/edgar/data/1439222/000119312525096719/d838751ddef14a.htm). - alpha:projection-evidence:document:436b1d05cbd3cedd2e436645f41876bb99d84c3e889f2f05fcd47f38c1499d2d: [sec_proxy](https://www.sec.gov/Archives/edgar/data/1359931/000121390025035568/ea0239092-01.htm). - alpha:projection-evidence:03e37199347a641e01211612cd6672100c83aa615de7c781e844abd2f2f078cf: [public_source](https://www.sec.gov/Archives/edgar/data/1346830/000110465926047695/tvrd-20260609xdef14a.htm). - alpha:projection-evidence:349feaafa56c296ebf6b934eb4adf6ba16ae6176f83e79582c977b4e75f62486: [public_source](https://www.sec.gov/Archives/edgar/data/1439222/000119312525096719/d838751ddef14a.htm). - alpha:projection-evidence:847fad036ba319aa19100716b06206bbe60c404b5d9c77c8bbf36dc621224545: [public_source](https://www.sec.gov/Archives/edgar/data/1359931/000121390025035568/ea0239092-01.htm). - alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71: [public_source](https://www.sec.gov/Archives/edgar/data/1701108/000119312525100544/d797305ddef14a.htm). - alpha:projection-evidence:86261273562f67a01dba081b1ef5e65d436cae1d10d74d002b2970a6c40c68c2: [public_source](https://www.sec.gov/Archives/edgar/data/1517022/000151702225000023/akba-20250429.htm). ## Rights | Field | Value | | --- | --- | | public_retrieval | allowed | | agent_retrieval | allowed | | redistribution | not_granted | | model_training | not_granted | | commercial_use | not_specified | | relationship_pathfinding | not_granted | | direct_contact | not_granted | ## Limitations - Only permissioned public claims and evidence are included. - Absence of a claim is not evidence that the underlying fact is false. - Public retrieval does not grant model-training or redistribution rights. - Private relationships and Council activity are excluded. ## Alternate representations - [Canonical profile](https://registry.alpha.ac/people/cynthia-smith) - [Public Markdown](https://registry.alpha.ac/people/cynthia-smith.md) - [Public JSON](https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=record) - [JSON-LD](https://registry.alpha.ac/api/public/profiles/cynthia-smith?format=jsonld) - MCP resource: `alpha://people/cynthia-smith` at https://mcp.alpha.ac/mcp ## Connected governance records Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage.