# Spero Therapeutics, Inc.

> Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero.

## Record

| Field | Value |
| --- | --- |
| Representation | alpha-profile-markdown-v4 |
| Protocol | Alpha Governance Facts Protocol 0.1 |
| Schema | alpha.governance.entity.public.v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| Governance record representation | alpha-governance-record-v2 |
| Canonical entity | alpha:company:73c14dd4-c511-4915-b606-f728a4c281c3 |
| Entity type | Company |
| Canonical URL | https://registry.alpha.ac/companies/spero-therapeutics-inc |
| Publication | PUBLISHED |
| Verification | source_reported |
| Verification schema | alpha-verification-states-v1 |
| Ownership | unclaimed |
| Published claims | 23 |
| Claims under review | 1 |
| Evidence records | 3 |
| Conflicts | 0 |
| Conflicts in internal review | 0 |
| Observed | 2026-10-16T13:53:12.75153+00:00 |
| Last reviewed | 2026-10-16T13:53:12.75153+00:00 |

## Identity

- Legal name: Spero Therapeutics, Inc.
- Display name: Spero Therapeutics, Inc.

## Alpha Governance Record

| Field | Value |
| --- | --- |
| Governance Record schema | alpha-governance-record-v2 |
| Ontology | alpha-governance-ontology-v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| As of | 2026-10-17T04:39:31.386941+00:00 |
| Completeness | 0.364 |
| Record Quality | 0.832 |
| Directors | 9 |
| Committees | 6 |
| Governance events | 16 |
| Entity class | public_company |

## Section coverage

| Section | State |
| --- | --- |
| identity | PUBLISHED |
| corporate_structure | NOT_REVIEWED |
| board | PUBLISHED |
| committees | PUBLISHED |
| leadership | NOT_REVIEWED |
| ownership | NOT_REVIEWED |
| financials | NOT_REVIEWED |
| capital_structure | PUBLISHED |
| compensation | NOT_REVIEWED |
| governance | NOT_REVIEWED |
| shareholder_governance | NOT_REVIEWED |
| audit | NOT_REVIEWED |
| legal | NOT_REVIEWED |
| risk | NOT_REVIEWED |
| cyber | NOT_REVIEWED |
| ai_governance | NOT_REVIEWED |
| agent_governance | RESTRICTED |
| markets_external | NOT_REVIEWED |
| events | PUBLISHED |
| relationships | PUBLISHED |
| assessments | PUBLISHED |
| evidence | PUBLISHED |

## Board

- Ankit Mahadevia, M.D.: Director. Status: current. Independent: false. Since: 2013-01-01. claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:7
- Cynthia Smith: Director. Status: current. Independent: true. Since: 2019-01-01. Committees: Compensation (chair); Compensation · Chair (member). claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:8
- Esther Rajavelu: Director. Status: current. Independent: false. Since: 2025-01-01. claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:9
- Frank E. Thomas: Director. Status: current. Independent: true. Since: 2017-01-01. Committees: Audit (chair); Audit · Chair (member). claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:10
- John C. Pottage, Jr., M.D.: Director. Status: current. Independent: true. Since: 2018-01-01. claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:11
- Kathleen Tregoning: Director. Status: current. Independent: true. Since: 2021-01-01. Committees: Compensation (member). claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:12
- Milind Deshpande, Ph.D.: Director. Status: current. Independent: true. Since: 2014-01-01. claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:13
- Patrick Vink, M.D.: Director. Status: current. Independent: true. Since: 2015-01-01. claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:14
- Sharon L. Jackson: Director. Status: current. Independent: true. Since: 2020-01-01. Committees: Audit (member); Audit; Nominating and Governance (member); Nominating and Governance (member). claim_id=alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:15

## Committees

- Audit (audit). Chair: Frank E. Thomas. Members: Frank E. Thomas (chair, current); Sharon L. Jackson (member, current). committee_id=alpha:committee:spero-therapeutics-inc:audit
- Audit · Chair (audit). Chair: NOT_PUBLISHED. Members: Frank E. Thomas (member, current). committee_id=alpha:committee:spero-therapeutics-inc:audit-chair
- Audit; Nominating and Governance (audit). Chair: NOT_PUBLISHED. Members: Sharon L. Jackson (member, current). committee_id=alpha:committee:spero-therapeutics-inc:audit-nominating-and-governance
- Compensation (compensation). Chair: Cynthia Smith. Members: Cynthia Smith (chair, current); Kathleen Tregoning (member, current). committee_id=alpha:committee:spero-therapeutics-inc:compensation
- Compensation · Chair (compensation). Chair: NOT_PUBLISHED. Members: Cynthia Smith (member, current). committee_id=alpha:committee:spero-therapeutics-inc:compensation-chair
- Nominating and Governance (nominating_governance). Chair: NOT_PUBLISHED. Members: Sharon L. Jackson (member, current). committee_id=alpha:committee:spero-therapeutics-inc:nominating-and-governance

## Governance events

- DIRECTOR_APPOINTED: Esther Rajavelu seat on Spero Therapeutics, Inc., effective 2025-01-01. Effective: 2025-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:16rjw2914r0s9
- DIRECTOR_APPOINTED: Kathleen Tregoning seat on Spero Therapeutics, Inc., effective 2021-01-01. Effective: 2021-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:ilccandfe15j
- COMMITTEE_MEMBER_ADDED: Kathleen Tregoning member of Compensation, effective 2021-01-01. Effective: 2021-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:18x2itovnyud
- DIRECTOR_APPOINTED: Sharon L. Jackson seat on Spero Therapeutics, Inc., effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1x38837np7vx
- COMMITTEE_CREATED: Audit; Nominating and Governance committee of Spero Therapeutics, Inc., effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:7ryg11djdw8x
- COMMITTEE_MEMBER_ADDED: Sharon L. Jackson member of Audit; Nominating and Governance, effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1mi7tf11q5unh7
- DIRECTOR_APPOINTED: Cynthia Smith seat on Spero Therapeutics, Inc., effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1ywlri11vyf2v7
- COMMITTEE_CREATED: Compensation · Chair committee of Spero Therapeutics, Inc., effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:gaan8p78a6b
- COMMITTEE_MEMBER_ADDED: Cynthia Smith member of Compensation · Chair, effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:co3axq17b5ti2
- DIRECTOR_APPOINTED: John C. Pottage, Jr., M.D. seat on Spero Therapeutics, Inc., effective 2018-01-01. Effective: 2018-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1rtews21br210u
- DIRECTOR_APPOINTED: Frank E. Thomas seat on Spero Therapeutics, Inc., effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:5vx75e1kvrfws
- COMMITTEE_CREATED: Audit · Chair committee of Spero Therapeutics, Inc., effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1r6bprm1t0y0k4
- COMMITTEE_MEMBER_ADDED: Frank E. Thomas member of Audit · Chair, effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:18rglmkelq94s
- DIRECTOR_APPOINTED: Patrick Vink, M.D. seat on Spero Therapeutics, Inc., effective 2015-01-01. Effective: 2015-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:u5lm8s1wsqmnu
- DIRECTOR_APPOINTED: Milind Deshpande, Ph.D. seat on Spero Therapeutics, Inc., effective 2014-01-01. Effective: 2014-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:8usm8wh0ffjs
- DIRECTOR_APPOINTED: Ankit Mahadevia, M.D. seat on Spero Therapeutics, Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:12.75153+00:00. event_id=alpha:event:transition:1y5tug430tjfy

## Scoped resources

- `alpha://company/spero-therapeutics-inc` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record
- `alpha://company/spero-therapeutics-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=identity
- `alpha://company/spero-therapeutics-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=corporate-structure
- `alpha://company/spero-therapeutics-inc/board` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=board
- `alpha://company/spero-therapeutics-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=committees
- `alpha://company/spero-therapeutics-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=leadership
- `alpha://company/spero-therapeutics-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=ownership
- `alpha://company/spero-therapeutics-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=financials
- `alpha://company/spero-therapeutics-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=capital-structure
- `alpha://company/spero-therapeutics-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=compensation
- `alpha://company/spero-therapeutics-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=governance
- `alpha://company/spero-therapeutics-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=shareholder-governance
- `alpha://company/spero-therapeutics-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=audit
- `alpha://company/spero-therapeutics-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=legal
- `alpha://company/spero-therapeutics-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=risk
- `alpha://company/spero-therapeutics-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=cyber
- `alpha://company/spero-therapeutics-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=ai-governance
- `alpha://company/spero-therapeutics-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=agents
- `alpha://company/spero-therapeutics-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=ecosystem
- `alpha://company/spero-therapeutics-inc/events` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=events
- `alpha://company/spero-therapeutics-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=relationships
- `alpha://company/spero-therapeutics-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=assessments
- `alpha://company/spero-therapeutics-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record&section=evidence

## Role modules

- NOT_ASSERTED

## Attention

- NO_RECORDS_FOUND

## Committee data

- Claim alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:17: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"chair","person":{"alpha_id":"alpha:person:frank-e-thomas","name":"Frank E. Thomas"},"source_id":"board_seats"}`
- Claim alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:18: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"member","person":{"alpha_id":"alpha:person:scott-jackson","name":"Sharon L. Jackson"},"source_id":"board_seats"}`
- Claim alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:20: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"chair","person":{"alpha_id":"alpha:person:cynthia-smith","name":"Cynthia Smith"},"source_id":"board_seats"}`
- Claim alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:21: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:kathleen-tregoning","name":"Kathleen Tregoning"},"source_id":"board_seats"}`
- Claim alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:23: `{"kind":"committee_appointment","original_name":"Nominating and Governance","category":"nominating_governance","role":"member","person":{"alpha_id":"alpha:person:scott-jackson","name":"Sharon L. Jackson"},"source_id":"board_seats"}`

## Leadership

- Ankit Mahadevia, M.D.: Director. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:7. Valid from: 2013-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Cynthia Smith: Director, Compensation · Chair. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:8. Valid from: 2019-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Esther Rajavelu: Director. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:9. Valid from: 2025-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Frank E. Thomas: Director, Audit · Chair. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:10. Valid from: 2017-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- John C. Pottage, Jr., M.D.: Director. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:11. Valid from: 2018-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Kathleen Tregoning: Director, Compensation. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:12. Valid from: 2021-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Milind Deshpande, Ph.D.: Director. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:13. Valid from: 2014-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Patrick Vink, M.D.: Director. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:14. Valid from: 2015-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.
- Sharon L. Jackson: Director, Audit; Nominating and Governance. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:leadership_role:15. Valid from: 2020-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c.

## Roles

- PUBLISHED

## Governance

- NOT_ASSERTED

## Board committees

- Audit: Chair Frank E. Thomas; Members Frank E. Thomas (Chair); Sharon L. Jackson. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_record:16. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Compensation: Chair Cynthia Smith; Members Cynthia Smith (Chair); Kathleen Tregoning. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_record:19. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Nominating and Governance: Chair not stated; Members Sharon L. Jackson. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_record:22. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.

## Financials

- NOT_ASSERTED

## Workforce

- NOT_ASSERTED

## Market and index context

- PUBLISHED

## Legal Name

- Spero Therapeutics, Inc.. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.

## Entity Status

- Public listing published. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.

## Published Fact

- US. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.
- Healthcare. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:published_fact:5. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.
- Biotechnology. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:published_fact:6. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.

## Committee Appointment

- Frank E. Thomas: chair, Audit. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:17. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Sharon L. Jackson: member, Audit. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:18. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Cynthia Smith: chair, Compensation. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:20. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Kathleen Tregoning: member, Compensation. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:21. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.
- Sharon L. Jackson: member, Nominating and Governance. Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:committee_appointment:23. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71.

## Security Listing

- SPRO (NASDAQ). Claim: alpha:claim:company:73c14dd4-c511-4915-b606-f728a4c281c3:security_listing:24. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156.

## Coverage states

| Field | Value |
| --- | --- |
| Identity | PUBLISHED |
| Business | PUBLISHED |
| Leadership | PUBLISHED |
| Board and committees | PUBLISHED |
| Governance | NOT_ASSERTED |
| Financials | NOT_ASSERTED |
| Workforce | NOT_ASSERTED |
| Ownership | NOT_ASSERTED |
| Ratings | NOT_PUBLISHED |
| Market and index context | PUBLISHED |

## Public sources

- alpha:projection-evidence:0fae3f4ca4bd2b87e39da28de4704d4bd675ba03d9b7f5ac42a5f71cadc25156: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/spero-therapeutics-inc).
- alpha:projection-evidence:document:faf3b03068a37efd6984d9a88af8c10ed035d245c231450f37208b17c3d8724c: [Spero Therapeutics, Inc. DEF 14A 2025-04-28](https://www.sec.gov/Archives/edgar/data/1701108/000119312525100544/d797305ddef14a.htm).
- alpha:projection-evidence:ce4ab61dbd7871fc39f3fe601ad1ae0a4a98b664435ec6e6a47498defe6f2e71: [Audit](https://www.sec.gov/Archives/edgar/data/1701108/000119312525100544/d797305ddef14a.htm).

## Rights

| Field | Value |
| --- | --- |
| public_retrieval | allowed |
| agent_retrieval | allowed |
| redistribution | not_granted |
| model_training | not_granted |
| commercial_use | not_specified |
| relationship_pathfinding | not_granted |
| direct_contact | not_granted |

## Limitations

- Absence of a leadership role, committee, or disclosure is not evidence that it does not exist.
- Only explicitly published canonical company identity and current confirmed public roles are included.
- Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist.
- Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights.
- This Company Profile is an identity and evidence record, not an Alpha rating.

## Alternate representations

- [Canonical profile](https://registry.alpha.ac/companies/spero-therapeutics-inc)
- [Public Markdown](https://registry.alpha.ac/companies/spero-therapeutics-inc.md)
- [Public JSON](https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=record)
- [JSON-LD](https://registry.alpha.ac/api/public/companies/spero-therapeutics-inc?format=jsonld)
- MCP resource: `alpha://companies/spero-therapeutics-inc` at https://mcp.alpha.ac/mcp


## Connected governance records

Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage.

## Critical-risk oversight

Snapshot as of 2026-10-17T04:39:31.194047+00:00; recorded 2026-10-17T04:39:31.194047+00:00. Every published assignment for this snapshot is listed.
Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording.
An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.