# OPKO HEALTH, INC. > Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero. ## Record | Field | Value | | --- | --- | | Representation | alpha-profile-markdown-v4 | | Protocol | Alpha Governance Facts Protocol 0.1 | | Schema | alpha.governance.entity.public.v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | Governance record representation | alpha-governance-record-v2 | | Canonical entity | alpha:company:b53442f5-cac3-4be9-85f7-e1b163a76c85 | | Entity type | Company | | Canonical URL | https://registry.alpha.ac/companies/opko-health-inc | | Publication | PUBLISHED | | Verification | source_reported | | Verification schema | alpha-verification-states-v1 | | Ownership | unclaimed | | Published claims | 24 | | Claims under review | 1 | | Evidence records | 4 | | Conflicts | 0 | | Conflicts in internal review | 0 | | Observed | 2026-10-17T04:46:12.142687+00:00 | | Last reviewed | 2026-10-17T04:46:12.142687+00:00 | ## Identity - Legal name: OPKO HEALTH, INC. - Display name: OPKO HEALTH, INC. ## Alpha Governance Record | Field | Value | | --- | --- | | Governance Record schema | alpha-governance-record-v2 | | Ontology | alpha-governance-ontology-v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | As of | 2026-10-17T10:52:06.667197+00:00 | | Completeness | 0.409 | | Record Quality | 0.814 | | Directors | 12 | | Committees | 1 | | Governance events | 2 | | Entity class | public_company | ## Section coverage | Section | State | | --- | --- | | identity | PUBLISHED | | corporate_structure | NOT_REVIEWED | | board | PUBLISHED | | committees | PUBLISHED | | leadership | PUBLISHED | | ownership | NOT_REVIEWED | | financials | NOT_REVIEWED | | capital_structure | PUBLISHED | | compensation | NOT_REVIEWED | | governance | NOT_REVIEWED | | shareholder_governance | NOT_REVIEWED | | audit | NOT_REVIEWED | | legal | NOT_REVIEWED | | risk | NOT_REVIEWED | | cyber | NOT_REVIEWED | | ai_governance | NOT_REVIEWED | | agent_governance | RESTRICTED | | markets_external | NOT_REVIEWED | | events | PUBLISHED | | relationships | PUBLISHED | | assessments | PUBLISHED | | evidence | PUBLISHED | ## Board - Phillip Frost: Director. Status: current. Independent: NOT_PUBLISHED. Since: 1983-01-01. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:11 - Richard C. Pfenniger, Jr: Director. Status: current. Independent: NOT_PUBLISHED. Since: 2008-01-01. Committees: Audit Committee (chair). claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:13 - Alice Lin-Tsing Yu, M.D., Ph.D.: Director. Status: unknown. Independent: true. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:6 - Elias A. Zerhouni, M.D.: Vice Chairman of the Board and President. Status: unknown. Independent: false. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:7 - Gary J. Nabel, M.D., Ph.D.: Director and Chief Innovation Officer. Status: unknown. Independent: false. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:8 - Jane H. Hsiao, Ph.D., MBA: Vice Chairman of the Board and Chief Technical Officer. Status: unknown. Independent: false. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:9 - John A. Paganelli: Director. Status: unknown. Independent: true. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:10 - Phillip Frost, M.D.: Chairman of the Board and Chief Executive Officer. Status: unknown. Independent: false. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:5 - Prem A. Lachman, M.D.: Director. Status: unknown. Independent: true. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:12 - Roger J. Medel, M.D.: Director. Status: unknown. Independent: true. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:14 - Steven D. Rubin: Director and Executive Vice President-Administration. Status: unknown. Independent: false. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:15 - Subbarao V. Uppaluri, Ph.D.: Director. Status: unknown. Independent: true. Since: NOT_PUBLISHED. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:16 ## Committees - Audit Committee (audit). Chair: Richard C. Pfenniger, Jr. Members: Richard C. Pfenniger, Jr (chair, current). committee_id=alpha:committee:opko-health-inc:audit-committee ## Executive leadership - Adam Logal: Senior Vice President, Chief Financial Officer, Chief Accounting Officer, and Treasurer [CFO]. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:17 - Elias A. Zerhouni, M.D.: President [PRESIDENT]. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:18 - Gary J. Nabel, M.D., Ph.D.: Chief Innovation Officer. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:19 - Jane H. Hsiao, Ph.D., MBA: Chief Technical Officer. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:20 - Phillip Frost, M.D.: Chief Executive Officer [CEO]. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:21 - Steven D. Rubin: Executive Vice President-Administration. Status: unknown. claim_id=alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:22 ## Governance events - DIRECTOR_APPOINTED: Richard C. Pfenniger, Jr seat on OPKO HEALTH, INC., effective 2008-01-01. Effective: 2008-01-01. Detected: 2026-10-17T04:46:12.142687+00:00. event_id=alpha:event:transition:1c1r36qh5xlba - DIRECTOR_APPOINTED: Phillip Frost seat on OPKO HEALTH, INC., effective 1983-01-01. Effective: 1983-01-01. Detected: 2026-10-17T04:46:12.142687+00:00. event_id=alpha:event:transition:1n09xplmjhr7h ## Scoped resources - `alpha://company/opko-health-inc` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record - `alpha://company/opko-health-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=identity - `alpha://company/opko-health-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=corporate-structure - `alpha://company/opko-health-inc/board` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=board - `alpha://company/opko-health-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=committees - `alpha://company/opko-health-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=leadership - `alpha://company/opko-health-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=ownership - `alpha://company/opko-health-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=financials - `alpha://company/opko-health-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=capital-structure - `alpha://company/opko-health-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=compensation - `alpha://company/opko-health-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=governance - `alpha://company/opko-health-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=shareholder-governance - `alpha://company/opko-health-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=audit - `alpha://company/opko-health-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=legal - `alpha://company/opko-health-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=risk - `alpha://company/opko-health-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=cyber - `alpha://company/opko-health-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=ai-governance - `alpha://company/opko-health-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=agents - `alpha://company/opko-health-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=ecosystem - `alpha://company/opko-health-inc/events` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=events - `alpha://company/opko-health-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=relationships - `alpha://company/opko-health-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=assessments - `alpha://company/opko-health-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record§ion=evidence ## Role modules - NOT_ASSERTED ## Attention - NO_RECORDS_FOUND ## Committee data - Claim alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:committee_appointment:24: `{"kind":"committee_appointment","original_name":"Audit Committee","category":"audit","role":"chair","person":{"alpha_id":"alpha:person:richard-c-pfenniger-jr-opk","name":"Richard C. Pfenniger, Jr"},"source_id":"governance_people_committees"}` ## Leadership - Phillip Frost, M.D.: Chairman of the Board and Chief Executive Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:5. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Alice Lin-Tsing Yu, M.D., Ph.D.: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:6. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Elias A. Zerhouni, M.D.: Vice Chairman of the Board and President. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:7. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Gary J. Nabel, M.D., Ph.D.: Director and Chief Innovation Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:8. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Jane H. Hsiao, Ph.D., MBA: Vice Chairman of the Board and Chief Technical Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:9. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - John A. Paganelli: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:10. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Phillip Frost: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:11. Valid from: 1983-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b455c520c88f81c5d1bcee474fe9b14d5215c67997093d93e264f5d8986a4503. - Prem A. Lachman, M.D.: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:12. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Richard C. Pfenniger, Jr: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:13. Valid from: 2008-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b455c520c88f81c5d1bcee474fe9b14d5215c67997093d93e264f5d8986a4503. - Roger J. Medel, M.D.: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:14. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Steven D. Rubin: Director and Executive Vice President-Administration. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:15. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Subbarao V. Uppaluri, Ph.D.: Director. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:16. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Adam Logal: Senior Vice President, Chief Financial Officer, Chief Accounting Officer, and Treasurer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:17. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Elias A. Zerhouni, M.D.: President. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:18. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Gary J. Nabel, M.D., Ph.D.: Chief Innovation Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:19. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Jane H. Hsiao, Ph.D., MBA: Chief Technical Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:20. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Phillip Frost, M.D.: Chief Executive Officer. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:21. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. - Steven D. Rubin: Executive Vice President-Administration. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:leadership_role:22. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d. ## Roles - PUBLISHED ## Governance - NOT_ASSERTED ## Board committees - Audit Committee: Chair Richard C. Pfenniger, Jr; Members Richard C. Pfenniger, Jr (Chair). Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:committee_record:23. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:5716ae13b45ed4439d02b310506ec01bfd318b92c458b4d3ec39047074f874a5. ## Financials - NOT_ASSERTED ## Workforce - NOT_ASSERTED ## Market and index context - PUBLISHED ## Legal Name - OPKO HEALTH, INC.. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e2f9dadc3f8c4c7522a35852f27e1df71a589eccd86c01c3156cfd80022fbb56. ## Entity Status - Public listing published. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e2f9dadc3f8c4c7522a35852f27e1df71a589eccd86c01c3156cfd80022fbb56. ## Published Fact - US. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e2f9dadc3f8c4c7522a35852f27e1df71a589eccd86c01c3156cfd80022fbb56. ## Committee Appointment - Richard C. Pfenniger, Jr: chair, Audit Committee. Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:committee_appointment:24. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:5716ae13b45ed4439d02b310506ec01bfd318b92c458b4d3ec39047074f874a5. ## Security Listing - OPK (NASDAQ). Claim: alpha:claim:company:b53442f5-cac3-4be9-85f7-e1b163a76c85:security_listing:25. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e2f9dadc3f8c4c7522a35852f27e1df71a589eccd86c01c3156cfd80022fbb56. ## Coverage states | Field | Value | | --- | --- | | Identity | PUBLISHED | | Business | PUBLISHED | | Leadership | PUBLISHED | | Board and committees | PUBLISHED | | Governance | NOT_ASSERTED | | Financials | NOT_ASSERTED | | Workforce | NOT_ASSERTED | | Ownership | NOT_ASSERTED | | Ratings | NOT_PUBLISHED | | Market and index context | PUBLISHED | ## Public sources - alpha:projection-evidence:e2f9dadc3f8c4c7522a35852f27e1df71a589eccd86c01c3156cfd80022fbb56: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/opko-health-inc). - alpha:projection-evidence:document:6dcdf13c80e805fe06022d11d8ffa10256e6d212c8c27887c8b0ab0cce8e7e9d: [SEC DEF 14A 0001193125-26-197120](https://www.sec.gov/Archives/edgar/data/944809/000119312526197120/opk-20260430.htm). - alpha:projection-evidence:document:b455c520c88f81c5d1bcee474fe9b14d5215c67997093d93e264f5d8986a4503: [DEF 14A opk-20260430.htm](https://www.sec.gov/Archives/edgar/data/944809/000119312526197120/opk-20260430.htm). - alpha:projection-evidence:5716ae13b45ed4439d02b310506ec01bfd318b92c458b4d3ec39047074f874a5: [Audit Committee](https://www.sec.gov/Archives/edgar/data/944809/000119312526197120/opk-20260430.htm). ## Rights | Field | Value | | --- | --- | | public_retrieval | allowed | | agent_retrieval | allowed | | redistribution | not_granted | | model_training | not_granted | | commercial_use | not_specified | | relationship_pathfinding | not_granted | | direct_contact | not_granted | ## Limitations - Absence of a leadership role, committee, or disclosure is not evidence that it does not exist. - Only explicitly published canonical company identity and current confirmed public roles are included. - Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist. - Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights. - This Company Profile is an identity and evidence record, not an Alpha rating. ## Alternate representations - [Canonical profile](https://registry.alpha.ac/companies/opko-health-inc) - [Public Markdown](https://registry.alpha.ac/companies/opko-health-inc.md) - [Public JSON](https://registry.alpha.ac/api/public/companies/opko-health-inc?format=record) - [JSON-LD](https://registry.alpha.ac/api/public/companies/opko-health-inc?format=jsonld) - MCP resource: `alpha://companies/opko-health-inc` at https://mcp.alpha.ac/mcp ## Connected governance records Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage. ## Critical-risk oversight Snapshot as of 2026-10-17T10:52:06.459911+00:00; recorded 2026-10-17T10:52:06.459911+00:00. Every published assignment for this snapshot is listed. Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording. An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.