# OnKure Therapeutics, Inc. > Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero. ## Record | Field | Value | | --- | --- | | Representation | alpha-profile-markdown-v4 | | Protocol | Alpha Governance Facts Protocol 0.1 | | Schema | alpha.governance.entity.public.v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | Governance record representation | alpha-governance-record-v2 | | Canonical entity | alpha:company:1133e5d6-69fa-410a-a614-699caacd4bcc | | Entity type | Company | | Canonical URL | https://registry.alpha.ac/companies/onkure-therapeutics-inc | | Publication | PUBLISHED | | Verification | source_reported | | Verification schema | alpha-verification-states-v1 | | Ownership | unclaimed | | Published claims | 23 | | Claims under review | 1 | | Evidence records | 8 | | Conflicts | 0 | | Conflicts in internal review | 0 | | Observed | 2026-10-16T13:53:08.730534+00:00 | | Last reviewed | 2026-10-16T13:53:08.730534+00:00 | ## Identity - Legal name: OnKure Therapeutics, Inc. - Display name: OnKure Therapeutics, Inc. ## Alpha Governance Record | Field | Value | | --- | --- | | Governance Record schema | alpha-governance-record-v2 | | Ontology | alpha-governance-ontology-v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | As of | 2026-10-17T02:37:04.021982+00:00 | | Completeness | 0.409 | | Record Quality | 0.846 | | Directors | 8 | | Committees | 3 | | Governance events | 16 | | Entity class | public_company | ## Section coverage | Section | State | | --- | --- | | identity | PUBLISHED | | corporate_structure | NOT_REVIEWED | | board | PUBLISHED | | committees | PUBLISHED | | leadership | PUBLISHED | | ownership | NOT_REVIEWED | | financials | NOT_REVIEWED | | capital_structure | PUBLISHED | | compensation | NOT_REVIEWED | | governance | NOT_REVIEWED | | shareholder_governance | NOT_REVIEWED | | audit | NOT_REVIEWED | | legal | NOT_REVIEWED | | risk | NOT_REVIEWED | | cyber | NOT_REVIEWED | | ai_governance | NOT_REVIEWED | | agent_governance | RESTRICTED | | markets_external | NOT_REVIEWED | | events | PUBLISHED | | relationships | PUBLISHED | | assessments | PUBLISHED | | evidence | PUBLISHED | ## Board - Andrew Phillips, Ph.D.: Director. Status: current. Independent: true. Since: 2024-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:5 - Edward T. Mathers: Director. Status: current. Independent: true. Since: 2017-01-01. Committees: Audit (member); Audit; Compensation (member); Compensation (member). claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:6 - Isaac Manke, Ph.D.: Director. Status: current. Independent: false. Since: 2024-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:7 - Liam Ratcliffe, M.D., Ph.D.: Director. Status: current. Independent: true. Since: 2026-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:8 - Michael Grey: Director. Status: current. Independent: false. Since: 2017-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:9 - Nicholas A. Saccomano, Ph.D.: Director. Status: current. Independent: false. Since: 2024-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:10 - R. Michael Carruthers: Director. Status: current. Independent: true. Since: 2024-01-01. Committees: Audit (member); Audit; Compensation (member); Compensation (member). claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:11 - Valerie M. Jansen, M.D., Ph.D.: Director. Status: current. Independent: true. Since: 2024-01-01. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:12 ## Committees - Audit (audit). Chair: NOT_PUBLISHED. Members: Edward T. Mathers (member, current); R. Michael Carruthers (member, current). committee_id=alpha:committee:onkure-therapeutics-inc:audit - Audit; Compensation (audit). Chair: NOT_PUBLISHED. Members: Edward T. Mathers (member, current); R. Michael Carruthers (member, current). committee_id=alpha:committee:onkure-therapeutics-inc:audit-compensation - Compensation (compensation). Chair: NOT_PUBLISHED. Members: Edward T. Mathers (member, current); R. Michael Carruthers (member, current). committee_id=alpha:committee:onkure-therapeutics-inc:compensation ## Executive leadership - Dylan Hartley, Ph.D.: Chief Scientific Officer. Status: current. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:13 - Isaac Manke, Ph.D.: Senior Vice President, Business Development. Status: current. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:14 - Jason Leverone, C.P.A.: Chief Financial Officer [CFO]. Status: current. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:15 - Nicholas A. Saccomano, Ph.D.: President and Chief Executive Officer [CEO]. Status: current. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:16 - Samuel Agresta, M.D.: Chief Medical Officer. Status: current. claim_id=alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:17 ## Governance events - EXECUTIVE_APPOINTED: Dylan Hartley, Ph.D. executive of OnKure Therapeutics, Inc., effective 2026-03-12. Effective: 2026-03-12. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:m3tr3k114o8t0 - EXECUTIVE_APPOINTED: Isaac Manke, Ph.D. executive of OnKure Therapeutics, Inc., effective 2026-03-12. Effective: 2026-03-12. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:vl28dr1930ip9 - CFO_CHANGED: Jason Leverone, C.P.A. executive of OnKure Therapeutics, Inc., effective 2026-03-12. Effective: 2026-03-12. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:kvnv0svefjpq - CEO_CHANGED: Nicholas A. Saccomano, Ph.D. executive of OnKure Therapeutics, Inc., effective 2026-03-12. Effective: 2026-03-12. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:11uloxfn72pxb - EXECUTIVE_APPOINTED: Samuel Agresta, M.D. executive of OnKure Therapeutics, Inc., effective 2026-03-12. Effective: 2026-03-12. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:1cn5rm61nlwg - DIRECTOR_APPOINTED: Liam Ratcliffe, M.D., Ph.D. seat on OnKure Therapeutics, Inc., effective 2026-01-01. Effective: 2026-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:1shzp9yyid0g0 - DIRECTOR_APPOINTED: Andrew Phillips, Ph.D. seat on OnKure Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:650q9t16on50v - DIRECTOR_APPOINTED: Isaac Manke, Ph.D. seat on OnKure Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:1rlm4xnmm6nth - DIRECTOR_APPOINTED: Nicholas A. Saccomano, Ph.D. seat on OnKure Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:1enbt6bdm4u3r - DIRECTOR_APPOINTED: R. Michael Carruthers seat on OnKure Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:126sj0k1vws64a - DIRECTOR_APPOINTED: Valerie M. Jansen, M.D., Ph.D. seat on OnKure Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:ssp71n1you8z5 - COMMITTEE_MEMBER_ADDED: R. Michael Carruthers member of Audit; Compensation, effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:m198bf1i5nm1x - DIRECTOR_APPOINTED: Edward T. Mathers seat on OnKure Therapeutics, Inc., effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:evxple1veax1g - DIRECTOR_APPOINTED: Michael Grey seat on OnKure Therapeutics, Inc., effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:cw14zfieyki7 - COMMITTEE_CREATED: Audit; Compensation committee of OnKure Therapeutics, Inc., effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:2r9s521ok3wc4 - COMMITTEE_MEMBER_ADDED: Edward T. Mathers member of Audit; Compensation, effective 2017-01-01. Effective: 2017-01-01. Detected: 2026-10-16T13:53:08.730534+00:00. event_id=alpha:event:transition:y6rd5btgx3tb ## Scoped resources - `alpha://company/onkure-therapeutics-inc` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record - `alpha://company/onkure-therapeutics-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=identity - `alpha://company/onkure-therapeutics-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=corporate-structure - `alpha://company/onkure-therapeutics-inc/board` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=board - `alpha://company/onkure-therapeutics-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=committees - `alpha://company/onkure-therapeutics-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=leadership - `alpha://company/onkure-therapeutics-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=ownership - `alpha://company/onkure-therapeutics-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=financials - `alpha://company/onkure-therapeutics-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=capital-structure - `alpha://company/onkure-therapeutics-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=compensation - `alpha://company/onkure-therapeutics-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=governance - `alpha://company/onkure-therapeutics-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=shareholder-governance - `alpha://company/onkure-therapeutics-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=audit - `alpha://company/onkure-therapeutics-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=legal - `alpha://company/onkure-therapeutics-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=risk - `alpha://company/onkure-therapeutics-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=cyber - `alpha://company/onkure-therapeutics-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=ai-governance - `alpha://company/onkure-therapeutics-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=agents - `alpha://company/onkure-therapeutics-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=ecosystem - `alpha://company/onkure-therapeutics-inc/events` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=events - `alpha://company/onkure-therapeutics-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=relationships - `alpha://company/onkure-therapeutics-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=assessments - `alpha://company/onkure-therapeutics-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record§ion=evidence ## Role modules - NOT_ASSERTED ## Attention - NO_RECORDS_FOUND ## Committee data - Claim alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:19: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"member","person":{"alpha_id":"alpha:person:edward-t-mathers","name":"Edward T. Mathers"},"source_id":"board_seats"}` - Claim alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:20: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"member","person":{"alpha_id":"alpha:person:r-michael-carruthers","name":"R. Michael Carruthers"},"source_id":"board_seats"}` - Claim alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:22: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:edward-t-mathers","name":"Edward T. Mathers"},"source_id":"board_seats"}` - Claim alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:23: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:r-michael-carruthers","name":"R. Michael Carruthers"},"source_id":"board_seats"}` ## Leadership - Andrew Phillips, Ph.D.: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:5. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Edward T. Mathers: Director, Audit; Compensation. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:6. Valid from: 2017-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Isaac Manke, Ph.D.: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:7. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Liam Ratcliffe, M.D., Ph.D.: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:8. Valid from: 2026-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Michael Grey: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:9. Valid from: 2017-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Nicholas A. Saccomano, Ph.D.: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:10. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - R. Michael Carruthers: Director, Audit; Compensation. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:11. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Valerie M. Jansen, M.D., Ph.D.: Director. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:12. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a. - Dylan Hartley, Ph.D.: Chief Scientific Officer. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:13. Valid from: 2026-03-12. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:dd2ea82846845d6cfdd6eb3b994539b531b30e28f2744bafe014bece6451edc3. - Isaac Manke, Ph.D.: Senior Vice President, Business Development. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:14. Valid from: 2026-03-12. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:f68788d4654b5c6daf7b9852b3967e430fad467fa2caafd858ff238f11e825a0. - Jason Leverone, C.P.A.: Chief Financial Officer. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:15. Valid from: 2026-03-12. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:13bb82672cc44fe28c54d3261b34a0ca08354204a50ce8f92b9884913584a425. - Nicholas A. Saccomano, Ph.D.: President and Chief Executive Officer. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:16. Valid from: 2026-03-12. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:88ef8b79dde706af2fde2a3db25cb55a17bfe2a43119e4aeb844c6e16afbe7c0. - Samuel Agresta, M.D.: Chief Medical Officer. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:leadership_role:17. Valid from: 2026-03-12. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:1b68bd534e61a26ecfd0732cdddf8a578fbc118ec9e2aad8fbac023a111f92c8. ## Roles - PUBLISHED ## Governance - NOT_ASSERTED ## Board committees - Audit: Chair not stated; Members Edward T. Mathers; R. Michael Carruthers. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_record:18. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. - Compensation: Chair not stated; Members Edward T. Mathers; R. Michael Carruthers. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_record:21. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. ## Financials - NOT_ASSERTED ## Workforce - NOT_ASSERTED ## Market and index context - PUBLISHED ## Legal Name - OnKure Therapeutics, Inc.. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:95c152dd0cd6434328fd5b56b7d6f4151ac29952845a052ac4bcc54c5b10cb42. ## Entity Status - Public listing published. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:95c152dd0cd6434328fd5b56b7d6f4151ac29952845a052ac4bcc54c5b10cb42. ## Published Fact - US. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:95c152dd0cd6434328fd5b56b7d6f4151ac29952845a052ac4bcc54c5b10cb42. ## Committee Appointment - Edward T. Mathers: member, Audit. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:19. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. - R. Michael Carruthers: member, Audit. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:20. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. - Edward T. Mathers: member, Compensation. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:22. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. - R. Michael Carruthers: member, Compensation. Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:committee_appointment:23. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d. ## Security Listing - OKUR (NASDAQ). Claim: alpha:claim:company:1133e5d6-69fa-410a-a614-699caacd4bcc:security_listing:24. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:95c152dd0cd6434328fd5b56b7d6f4151ac29952845a052ac4bcc54c5b10cb42. ## Coverage states | Field | Value | | --- | --- | | Identity | PUBLISHED | | Business | PUBLISHED | | Leadership | PUBLISHED | | Board and committees | PUBLISHED | | Governance | NOT_ASSERTED | | Financials | NOT_ASSERTED | | Workforce | NOT_ASSERTED | | Ownership | NOT_ASSERTED | | Ratings | NOT_PUBLISHED | | Market and index context | PUBLISHED | ## Public sources - alpha:projection-evidence:95c152dd0cd6434328fd5b56b7d6f4151ac29952845a052ac4bcc54c5b10cb42: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/onkure-therapeutics-inc). - alpha:projection-evidence:document:b86e4d7058b26197e61111ef5a0da517688181e68ee708bb2d7e6db8ee10657a: [OnKure Therapeutics, Inc. DEF 14A 2026-04-21](https://www.sec.gov/Archives/edgar/data/1637715/000114036126015903/ny20066577x1_def14a.htm). - alpha:projection-evidence:document:dd2ea82846845d6cfdd6eb3b994539b531b30e28f2744bafe014bece6451edc3: [OKUR 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1637715/000119312526104147/okur-20251231.htm). - alpha:projection-evidence:document:f68788d4654b5c6daf7b9852b3967e430fad467fa2caafd858ff238f11e825a0: [OKUR 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1637715/000119312526104147/okur-20251231.htm). - alpha:projection-evidence:document:13bb82672cc44fe28c54d3261b34a0ca08354204a50ce8f92b9884913584a425: [OKUR 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1637715/000119312526104147/okur-20251231.htm). - alpha:projection-evidence:document:88ef8b79dde706af2fde2a3db25cb55a17bfe2a43119e4aeb844c6e16afbe7c0: [OKUR 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1637715/000119312526104147/okur-20251231.htm). - alpha:projection-evidence:document:1b68bd534e61a26ecfd0732cdddf8a578fbc118ec9e2aad8fbac023a111f92c8: [OKUR 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1637715/000119312526104147/okur-20251231.htm). - alpha:projection-evidence:33288ddaeab0ff432bab2bd2a73c09cf859462103be1098374a3b223024eab7d: [Audit](https://www.sec.gov/Archives/edgar/data/1637715/000114036126015903/ny20066577x1_def14a.htm). ## Rights | Field | Value | | --- | --- | | public_retrieval | allowed | | agent_retrieval | allowed | | redistribution | not_granted | | model_training | not_granted | | commercial_use | not_specified | | relationship_pathfinding | not_granted | | direct_contact | not_granted | ## Limitations - Absence of a leadership role, committee, or disclosure is not evidence that it does not exist. - Only explicitly published canonical company identity and current confirmed public roles are included. - Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist. - Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights. - This Company Profile is an identity and evidence record, not an Alpha rating. ## Alternate representations - [Canonical profile](https://registry.alpha.ac/companies/onkure-therapeutics-inc) - [Public Markdown](https://registry.alpha.ac/companies/onkure-therapeutics-inc.md) - [Public JSON](https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=record) - [JSON-LD](https://registry.alpha.ac/api/public/companies/onkure-therapeutics-inc?format=jsonld) - MCP resource: `alpha://companies/onkure-therapeutics-inc` at https://mcp.alpha.ac/mcp ## Connected governance records Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage. ## Critical-risk oversight Snapshot as of 2026-10-17T02:37:03.774389+00:00; recorded 2026-10-17T02:37:03.774389+00:00. Every published assignment for this snapshot is listed. Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording. An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.