# Karyopharm Therapeutics Inc.

> Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero.

## Record

| Field | Value |
| --- | --- |
| Representation | alpha-profile-markdown-v4 |
| Protocol | Alpha Governance Facts Protocol 0.1 |
| Schema | alpha.governance.entity.public.v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| Governance record representation | alpha-governance-record-v2 |
| Canonical entity | alpha:company:d9e3a59e-f440-41c2-966e-06e1ac24c545 |
| Entity type | Company |
| Canonical URL | https://registry.alpha.ac/companies/karyopharm-therapeutics-inc |
| Publication | PUBLISHED |
| Verification | source_reported |
| Verification schema | alpha-verification-states-v1 |
| Ownership | unclaimed |
| Published claims | 25 |
| Claims under review | 1 |
| Evidence records | 9 |
| Conflicts | 0 |
| Conflicts in internal review | 0 |
| Observed | 2026-10-16T13:53:41.002909+00:00 |
| Last reviewed | 2026-10-16T13:53:41.002909+00:00 |

## Identity

- Legal name: Karyopharm Therapeutics Inc.
- Display name: Karyopharm Therapeutics Inc.

## Alpha Governance Record

| Field | Value |
| --- | --- |
| Governance Record schema | alpha-governance-record-v2 |
| Ontology | alpha-governance-ontology-v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| As of | 2026-10-16T17:33:15.770778+00:00 |
| Completeness | 0.409 |
| Record Quality | 0.846 |
| Directors | 7 |
| Committees | 5 |
| Governance events | 17 |
| Entity class | public_company |

## Section coverage

| Section | State |
| --- | --- |
| identity | PUBLISHED |
| corporate_structure | NOT_REVIEWED |
| board | PUBLISHED |
| committees | PUBLISHED |
| leadership | PUBLISHED |
| ownership | NOT_REVIEWED |
| financials | NOT_REVIEWED |
| capital_structure | PUBLISHED |
| compensation | NOT_REVIEWED |
| governance | NOT_REVIEWED |
| shareholder_governance | NOT_REVIEWED |
| audit | NOT_REVIEWED |
| legal | NOT_REVIEWED |
| risk | NOT_REVIEWED |
| cyber | NOT_REVIEWED |
| ai_governance | NOT_REVIEWED |
| agent_governance | RESTRICTED |
| markets_external | NOT_REVIEWED |
| events | PUBLISHED |
| relationships | PUBLISHED |
| assessments | PUBLISHED |
| evidence | PUBLISHED |

## Board

- Barry E. Greene: Director. Status: current. Independent: true. Since: 2013-01-01. Committees: Compensation (member); Compensation; Nominating and Governance · Chair (member); Nominating and Governance (chair). claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:5
- Christy J. Oliger: Director. Status: current. Independent: true. Since: 2020-01-01. Committees: Compensation (member). claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:6
- Cynthia L. Anderson, CPA: Director. Status: current. Independent: true. Since: 2020-01-01. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:7
- Deepika R. Pakianathan, Ph.D.: Director. Status: current. Independent: true. Since: 2013-01-01. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:8
- Garen G. Bohlin: Director. Status: current. Independent: true. Since: 2013-01-01. Committees: Audit (chair); Audit · Chair; Nominating and Governance (member); Nominating and Governance (member). claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:9
- Richard Paulson, M.B.A.: Director. Status: current. Independent: false. Since: 2020-01-01. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:10
- Zhen Su, M.D., M.B.A.: Director. Status: current. Independent: true. Since: 2023-01-01. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:11

## Committees

- Audit (audit). Chair: Garen G. Bohlin. Members: Garen G. Bohlin (chair, current). committee_id=alpha:committee:karyopharm-therapeutics-inc:audit
- Audit · Chair; Nominating and Governance (audit). Chair: NOT_PUBLISHED. Members: Garen G. Bohlin (member, current). committee_id=alpha:committee:karyopharm-therapeutics-inc:audit-chair-nominating-and-governance
- Compensation (compensation). Chair: NOT_PUBLISHED. Members: Barry E. Greene (member, current); Christy J. Oliger (member, current). committee_id=alpha:committee:karyopharm-therapeutics-inc:compensation
- Compensation; Nominating and Governance · Chair (compensation). Chair: NOT_PUBLISHED. Members: Barry E. Greene (member, current). committee_id=alpha:committee:karyopharm-therapeutics-inc:compensation-nominating-and-governance-chair
- Nominating and Governance (nominating_governance). Chair: Barry E. Greene. Members: Barry E. Greene (chair, current); Garen G. Bohlin (member, current). committee_id=alpha:committee:karyopharm-therapeutics-inc:nominating-and-governance

## Executive leadership

- Lori Macomber, C.P.A.: Executive Vice President, Chief Financial Officer and Treasurer [CFO]. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:12
- Michael V. Greco, J.D.: Executive Vice President, Chief Legal Officer and Secretary [GC]. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:13
- Reshma Rangwala, M.D., Ph.D.: Executive Vice President, Chief Medical Officer. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:14
- Richard Paulson, M.B.A.: President and Chief Executive Officer [CEO]. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:15
- Sohanya Cheng, M.B.A.: Executive Vice President, Chief Commercial Officer. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:16
- Stuart Poulton: Executive Vice President, Chief Development Officer. Status: current. claim_id=alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:17

## Governance events

- CFO_CHANGED: Lori Macomber, C.P.A. executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:dg087jy0i5d5
- GC_CHANGED: Michael V. Greco, J.D. executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:1ly8mbdv96ctb
- EXECUTIVE_APPOINTED: Reshma Rangwala, M.D., Ph.D. executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:17jw31z18716kn
- CEO_CHANGED: Richard Paulson, M.B.A. executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:p9ze824jnlv4
- EXECUTIVE_APPOINTED: Sohanya Cheng, M.B.A. executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:fb5mle7dbyzu
- EXECUTIVE_APPOINTED: Stuart Poulton executive of Karyopharm Therapeutics Inc., effective 2026-02-13. Effective: 2026-02-13. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:15k4p1f1jemc1f
- DIRECTOR_APPOINTED: Zhen Su, M.D., M.B.A. seat on Karyopharm Therapeutics Inc., effective 2023-01-01. Effective: 2023-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:15oyqnq1qzzls
- DIRECTOR_APPOINTED: Christy J. Oliger seat on Karyopharm Therapeutics Inc., effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:1047dw92ag5wh
- DIRECTOR_APPOINTED: Cynthia L. Anderson, CPA seat on Karyopharm Therapeutics Inc., effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:xfx14u61fpjo
- DIRECTOR_APPOINTED: Richard Paulson, M.B.A. seat on Karyopharm Therapeutics Inc., effective 2020-01-01. Effective: 2020-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:1o24k72148ob26
- DIRECTOR_APPOINTED: Barry E. Greene seat on Karyopharm Therapeutics Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:m9mfh27tzypu
- DIRECTOR_APPOINTED: Deepika R. Pakianathan, Ph.D. seat on Karyopharm Therapeutics Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:16kpsm91gn3k37
- DIRECTOR_APPOINTED: Garen G. Bohlin seat on Karyopharm Therapeutics Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:18m6pdizn9nn2
- COMMITTEE_CREATED: Audit · Chair; Nominating and Governance committee of Karyopharm Therapeutics Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:354kvu1bfk9me
- COMMITTEE_MEMBER_ADDED: Garen G. Bohlin member of Audit · Chair; Nominating and Governance, effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:1xcbi9mftzz3q
- COMMITTEE_CREATED: Compensation; Nominating and Governance · Chair committee of Karyopharm Therapeutics Inc., effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:131p3ig1ehbzxy
- COMMITTEE_MEMBER_ADDED: Barry E. Greene member of Compensation; Nominating and Governance · Chair, effective 2013-01-01. Effective: 2013-01-01. Detected: 2026-10-16T13:53:41.002909+00:00. event_id=alpha:event:transition:punw15n2vtwn

## Scoped resources

- `alpha://company/karyopharm-therapeutics-inc` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record
- `alpha://company/karyopharm-therapeutics-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=identity
- `alpha://company/karyopharm-therapeutics-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=corporate-structure
- `alpha://company/karyopharm-therapeutics-inc/board` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=board
- `alpha://company/karyopharm-therapeutics-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=committees
- `alpha://company/karyopharm-therapeutics-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=leadership
- `alpha://company/karyopharm-therapeutics-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=ownership
- `alpha://company/karyopharm-therapeutics-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=financials
- `alpha://company/karyopharm-therapeutics-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=capital-structure
- `alpha://company/karyopharm-therapeutics-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=compensation
- `alpha://company/karyopharm-therapeutics-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=governance
- `alpha://company/karyopharm-therapeutics-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=shareholder-governance
- `alpha://company/karyopharm-therapeutics-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=audit
- `alpha://company/karyopharm-therapeutics-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=legal
- `alpha://company/karyopharm-therapeutics-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=risk
- `alpha://company/karyopharm-therapeutics-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=cyber
- `alpha://company/karyopharm-therapeutics-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=ai-governance
- `alpha://company/karyopharm-therapeutics-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=agents
- `alpha://company/karyopharm-therapeutics-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=ecosystem
- `alpha://company/karyopharm-therapeutics-inc/events` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=events
- `alpha://company/karyopharm-therapeutics-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=relationships
- `alpha://company/karyopharm-therapeutics-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=assessments
- `alpha://company/karyopharm-therapeutics-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record&section=evidence

## Role modules

- NOT_ASSERTED

## Attention

- NO_RECORDS_FOUND

## Committee data

- Claim alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:19: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"chair","person":{"alpha_id":"alpha:person:garen-g-bohlin","name":"Garen G. Bohlin"},"source_id":"board_seats"}`
- Claim alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:21: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:barry-e-greene","name":"Barry E. Greene"},"source_id":"board_seats"}`
- Claim alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:22: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:christy-j-oliger","name":"Christy J. Oliger"},"source_id":"board_seats"}`
- Claim alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:24: `{"kind":"committee_appointment","original_name":"Nominating and Governance","category":"nominating_governance","role":"chair","person":{"alpha_id":"alpha:person:barry-e-greene","name":"Barry E. Greene"},"source_id":"board_seats"}`
- Claim alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:25: `{"kind":"committee_appointment","original_name":"Nominating and Governance","category":"nominating_governance","role":"member","person":{"alpha_id":"alpha:person:garen-g-bohlin","name":"Garen G. Bohlin"},"source_id":"board_seats"}`

## Leadership

- Barry E. Greene: Director, Compensation; Nominating and Governance · Chair. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:5. Valid from: 2013-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Christy J. Oliger: Director, Compensation. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:6. Valid from: 2020-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Cynthia L. Anderson, CPA: Director. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:7. Valid from: 2020-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Deepika R. Pakianathan, Ph.D.: Director. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:8. Valid from: 2013-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Garen G. Bohlin: Director, Audit · Chair; Nominating and Governance. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:9. Valid from: 2013-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Richard Paulson, M.B.A.: Director. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:10. Valid from: 2020-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Zhen Su, M.D., M.B.A.: Director. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:11. Valid from: 2023-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848.
- Lori Macomber, C.P.A.: Executive Vice President, Chief Financial Officer and Treasurer. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:12. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:ef57edc74878702f0811eb60506abe98b397e61fcb61228ed2035004473d9998.
- Michael V. Greco, J.D.: Executive Vice President, Chief Legal Officer and Secretary. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:13. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:95bbbb22949333e43a16e220c74b7417526b35e1b53aad286439a1db79f79c02.
- Reshma Rangwala, M.D., Ph.D.: Executive Vice President, Chief Medical Officer. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:14. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:ebf994635e7040faf25c2ef37d8e18e57373479e98542000963e6ed2b050891a.
- Richard Paulson, M.B.A.: President and Chief Executive Officer. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:15. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:ec6923005a6d4380fe5376986884ab511b084d3bb22dd25f042ba65fc779d008.
- Sohanya Cheng, M.B.A.: Executive Vice President, Chief Commercial Officer. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:16. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:0841f28528460d822d6f959f89aab8cc5a5d337dacae3e05f24f140b17638969.
- Stuart Poulton: Executive Vice President, Chief Development Officer. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:leadership_role:17. Valid from: 2026-02-13. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:6c6525bd39c9f21f19eb60a5b1f4790da4f8b8945f73bd80caba6c66645d655e.

## Roles

- PUBLISHED

## Governance

- NOT_ASSERTED

## Board committees

- Audit: Chair Garen G. Bohlin; Members Garen G. Bohlin (Chair). Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_record:18. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Compensation: Chair not stated; Members Barry E. Greene; Christy J. Oliger. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_record:20. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Nominating and Governance: Chair Barry E. Greene; Members Barry E. Greene (Chair); Garen G. Bohlin. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_record:23. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.

## Financials

- NOT_ASSERTED

## Workforce

- NOT_ASSERTED

## Market and index context

- PUBLISHED

## Legal Name

- Karyopharm Therapeutics Inc.. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:6b1ea196221851ab87a4c9620fe4b0ab3d82f8050b13c0c5992d8578c4e1eb89.

## Entity Status

- Public listing published. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:6b1ea196221851ab87a4c9620fe4b0ab3d82f8050b13c0c5992d8578c4e1eb89.

## Published Fact

- US. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:6b1ea196221851ab87a4c9620fe4b0ab3d82f8050b13c0c5992d8578c4e1eb89.

## Committee Appointment

- Garen G. Bohlin: chair, Audit. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:19. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Barry E. Greene: member, Compensation. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:21. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Christy J. Oliger: member, Compensation. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:22. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Barry E. Greene: chair, Nominating and Governance. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:24. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.
- Garen G. Bohlin: member, Nominating and Governance. Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:committee_appointment:25. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986.

## Security Listing

- KPTI (NASDAQ). Claim: alpha:claim:company:d9e3a59e-f440-41c2-966e-06e1ac24c545:security_listing:26. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:6b1ea196221851ab87a4c9620fe4b0ab3d82f8050b13c0c5992d8578c4e1eb89.

## Coverage states

| Field | Value |
| --- | --- |
| Identity | PUBLISHED |
| Business | PUBLISHED |
| Leadership | PUBLISHED |
| Board and committees | PUBLISHED |
| Governance | NOT_ASSERTED |
| Financials | NOT_ASSERTED |
| Workforce | NOT_ASSERTED |
| Ownership | NOT_ASSERTED |
| Ratings | NOT_PUBLISHED |
| Market and index context | PUBLISHED |

## Public sources

- alpha:projection-evidence:6b1ea196221851ab87a4c9620fe4b0ab3d82f8050b13c0c5992d8578c4e1eb89: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/karyopharm-therapeutics-inc).
- alpha:projection-evidence:document:9aaa3bfde545b513f87fac96fac418194d49e78f3e4989e70e8cb3215fb03848: [Karyopharm Therapeutics Inc. DEF 14A 2026-04-13](https://www.sec.gov/Archives/edgar/data/1503802/000150380226000023/kpti-20260413.htm).
- alpha:projection-evidence:document:ef57edc74878702f0811eb60506abe98b397e61fcb61228ed2035004473d9998: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:document:95bbbb22949333e43a16e220c74b7417526b35e1b53aad286439a1db79f79c02: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:document:ebf994635e7040faf25c2ef37d8e18e57373479e98542000963e6ed2b050891a: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:document:ec6923005a6d4380fe5376986884ab511b084d3bb22dd25f042ba65fc779d008: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:document:0841f28528460d822d6f959f89aab8cc5a5d337dacae3e05f24f140b17638969: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:document:6c6525bd39c9f21f19eb60a5b1f4790da4f8b8945f73bd80caba6c66645d655e: [KPTI 10-K executive officers](https://www.sec.gov/Archives/edgar/data/1503802/000119312526049397/kpti-20251231.htm).
- alpha:projection-evidence:a75dd4830ad63d0088b8bda65efcd3c9d7aaf5d494c08f0ec845bc893acbd986: [Audit](https://www.sec.gov/Archives/edgar/data/1503802/000150380226000023/kpti-20260413.htm).

## Rights

| Field | Value |
| --- | --- |
| public_retrieval | allowed |
| agent_retrieval | allowed |
| redistribution | not_granted |
| model_training | not_granted |
| commercial_use | not_specified |
| relationship_pathfinding | not_granted |
| direct_contact | not_granted |

## Limitations

- Absence of a leadership role, committee, or disclosure is not evidence that it does not exist.
- Only explicitly published canonical company identity and current confirmed public roles are included.
- Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist.
- Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights.
- This Company Profile is an identity and evidence record, not an Alpha rating.

## Alternate representations

- [Canonical profile](https://registry.alpha.ac/companies/karyopharm-therapeutics-inc)
- [Public Markdown](https://registry.alpha.ac/companies/karyopharm-therapeutics-inc.md)
- [Public JSON](https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=record)
- [JSON-LD](https://registry.alpha.ac/api/public/companies/karyopharm-therapeutics-inc?format=jsonld)
- MCP resource: `alpha://companies/karyopharm-therapeutics-inc` at https://mcp.alpha.ac/mcp


## Connected governance records

Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage.

## Critical-risk oversight

Snapshot as of 2026-10-16T17:33:15.478654+00:00; recorded 2026-10-16T17:33:15.478654+00:00. Every published assignment for this snapshot is listed.
Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording.
An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.