# IONIS PHARMACEUTICALS INC

> Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero.

## Record

| Field | Value |
| --- | --- |
| Representation | alpha-profile-markdown-v4 |
| Protocol | Alpha Governance Facts Protocol 0.1 |
| Schema | alpha.governance.entity.public.v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| Governance record representation | alpha-governance-record-v2 |
| Canonical entity | alpha:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9 |
| Entity type | Company |
| Canonical URL | https://registry.alpha.ac/companies/ionis-pharmaceuticals-inc |
| Publication | PUBLISHED |
| Verification | source_reported |
| Verification schema | alpha-verification-states-v1 |
| Ownership | unclaimed |
| Published claims | 21 |
| Claims under review | 1 |
| Evidence records | 14 |
| Conflicts | 0 |
| Conflicts in internal review | 0 |
| Observed | 2026-10-17T04:45:37.386881+00:00 |
| Last reviewed | 2026-10-17T04:45:37.386881+00:00 |

## Identity

- Legal name: IONIS PHARMACEUTICALS INC
- Display name: IONIS PHARMACEUTICALS INC

## Alpha Governance Record

| Field | Value |
| --- | --- |
| Governance Record schema | alpha-governance-record-v2 |
| Ontology | alpha-governance-ontology-v1 |
| Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce |
| As of | 2026-10-17T09:44:42.354652+00:00 |
| Completeness | 0.409 |
| Record Quality | 0.845 |
| Directors | 2 |
| Committees | 1 |
| Governance events | 14 |
| Entity class | public_company |

## Section coverage

| Section | State |
| --- | --- |
| identity | PUBLISHED |
| corporate_structure | NOT_REVIEWED |
| board | PUBLISHED |
| committees | PUBLISHED |
| leadership | PUBLISHED |
| ownership | NOT_REVIEWED |
| financials | NOT_REVIEWED |
| capital_structure | PUBLISHED |
| compensation | NOT_REVIEWED |
| governance | NOT_REVIEWED |
| shareholder_governance | NOT_REVIEWED |
| audit | NOT_REVIEWED |
| legal | NOT_REVIEWED |
| risk | NOT_REVIEWED |
| cyber | NOT_REVIEWED |
| ai_governance | NOT_REVIEWED |
| agent_governance | RESTRICTED |
| markets_external | NOT_REVIEWED |
| events | PUBLISHED |
| relationships | PUBLISHED |
| assessments | PUBLISHED |
| evidence | PUBLISHED |

## Board

- Joan E. Herman: Director. Status: current. Independent: true. Since: 2019-01-01. Committees: Compensation (member). claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:6
- Spencer R. Berthelsen: Director. Status: current. Independent: true. Since: 2002-01-01. Committees: Compensation (member). claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:7

## Committees

- Compensation (compensation). Chair: NOT_PUBLISHED. Members: Joan E. Herman (member, current); Spencer R. Berthelsen (member, current). committee_id=alpha:committee:ionis-pharmaceuticals-inc:compensation

## Executive leadership

- Brett P. Monia: Chief Executive Officer [CEO]. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:8
- Brian Birchler: Executive Vice President, Corporate Development and Operations. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:9
- C. Frank Bennett: Executive Vice President, Chief Scientific Officer. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:10
- Elizabeth L. Hougen: Executive Vice President, Finance and Chief Financial Officer [CFO]. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:11
- Eric E. Swayze: Executive Vice President, Research. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:12
- Eugene Schneider: Executive Vice President, Chief Clinical Development and Operations Officer. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:13
- Holly Kordasiewicz: Executive Vice President, Chief Development Officer. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:14
- Joseph T. Baroldi: Executive Vice President, Chief Business Officer. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:15
- Kyle Jenne: Executive Vice President, Chief Global Product Strategy Officer. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:16
- Patrick R. O Neil: Executive Vice President, Chief Legal Officer, General Counsel and Corporate Secretary [GC]. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:17
- Shannon L. Devers: Executive Vice President, Chief Human Resources Officer [CHRO]. Status: current. claim_id=alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:18

## Governance events

- CEO_CHANGED: Brett P. Monia executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:eckqp1mopqtf
- EXECUTIVE_APPOINTED: Brian Birchler executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:1fp4uh71m76kb
- EXECUTIVE_APPOINTED: C. Frank Bennett executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:89ikae4dmyuc
- CFO_CHANGED: Elizabeth L. Hougen executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:liznjx5hv0tf
- EXECUTIVE_APPOINTED: Eric E. Swayze executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:laq1dvep5vbd
- EXECUTIVE_APPOINTED: Eugene Schneider executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:l1m7zpjpq44x
- EXECUTIVE_APPOINTED: Holly Kordasiewicz executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:1lcil21du8awt
- EXECUTIVE_APPOINTED: Joseph T. Baroldi executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:12elhbp1sxslh7
- EXECUTIVE_APPOINTED: Kyle Jenne executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:1vzah351y9tbu9
- GC_CHANGED: Patrick R. O Neil executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:14629ccqdvkgg
- EXECUTIVE_APPOINTED: Shannon L. Devers executive of IONIS PHARMACEUTICALS INC, effective 2026-04-23. Effective: 2026-04-23. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:1am1grf7nkg43
- DIRECTOR_APPOINTED: Joan E. Herman seat on IONIS PHARMACEUTICALS INC, effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:1vgvw1p1a6ret5
- COMMITTEE_MEMBER_ADDED: Joan E. Herman member of Compensation, effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:g2y5qerbpwbg
- DIRECTOR_APPOINTED: Spencer R. Berthelsen seat on IONIS PHARMACEUTICALS INC, effective 2002-01-01. Effective: 2002-01-01. Detected: 2026-10-17T04:45:37.386881+00:00. event_id=alpha:event:transition:17misjwu7os1i

## Scoped resources

- `alpha://company/ionis-pharmaceuticals-inc` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record
- `alpha://company/ionis-pharmaceuticals-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=identity
- `alpha://company/ionis-pharmaceuticals-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=corporate-structure
- `alpha://company/ionis-pharmaceuticals-inc/board` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=board
- `alpha://company/ionis-pharmaceuticals-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=committees
- `alpha://company/ionis-pharmaceuticals-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=leadership
- `alpha://company/ionis-pharmaceuticals-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=ownership
- `alpha://company/ionis-pharmaceuticals-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=financials
- `alpha://company/ionis-pharmaceuticals-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=capital-structure
- `alpha://company/ionis-pharmaceuticals-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=compensation
- `alpha://company/ionis-pharmaceuticals-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=governance
- `alpha://company/ionis-pharmaceuticals-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=shareholder-governance
- `alpha://company/ionis-pharmaceuticals-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=audit
- `alpha://company/ionis-pharmaceuticals-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=legal
- `alpha://company/ionis-pharmaceuticals-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=risk
- `alpha://company/ionis-pharmaceuticals-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=cyber
- `alpha://company/ionis-pharmaceuticals-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=ai-governance
- `alpha://company/ionis-pharmaceuticals-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=agents
- `alpha://company/ionis-pharmaceuticals-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=ecosystem
- `alpha://company/ionis-pharmaceuticals-inc/events` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=events
- `alpha://company/ionis-pharmaceuticals-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=relationships
- `alpha://company/ionis-pharmaceuticals-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=assessments
- `alpha://company/ionis-pharmaceuticals-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record&section=evidence

## Role modules

- NOT_ASSERTED

## Attention

- NO_RECORDS_FOUND

## Committee data

- Claim alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:committee_appointment:20: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:joan-e-herman","name":"Joan E. Herman"},"source_id":"board_seats"}`
- Claim alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:committee_appointment:21: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:spencer-r-berthelsen","name":"Spencer R. Berthelsen"},"source_id":"board_seats"}`

## Leadership

- Joan E. Herman: Director, Compensation. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:6. Valid from: 2019-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9b9f6a7411d44c1aa4fa09093d959ebf1b50fbb64c23ffb89a526dc9dfb08464.
- Spencer R. Berthelsen: Director, Compensation. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:7. Valid from: 2002-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9b9f6a7411d44c1aa4fa09093d959ebf1b50fbb64c23ffb89a526dc9dfb08464.
- Brett P. Monia: Chief Executive Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:8. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:49a71ce8bbffb84853586868d47cbc3e77adc02650d82db945180c0d50dcab42.
- Brian Birchler: Executive Vice President, Corporate Development and Operations. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:9. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:8878d4a5960ec580beffcc484bd84c83ce1c926f639f742368035874ac238f39.
- C. Frank Bennett: Executive Vice President, Chief Scientific Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:10. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:47e558adea11e378b979447f63aec41c7199f29a4065b8ebc0df83acc7255c81.
- Elizabeth L. Hougen: Executive Vice President, Finance and Chief Financial Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:11. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:dcb41d0451de496b35df284812771020df8fe78f5360bf95635657d4b916d6b2.
- Eric E. Swayze: Executive Vice President, Research. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:12. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:3ebb466a25fae76f35f4bd8f50c25f90a075b15dd38861ab88788b8cb638897c.
- Eugene Schneider: Executive Vice President, Chief Clinical Development and Operations Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:13. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:d1fc57a8f0c33dd4ca416b305f1ffce040f3cec171ad77044fe14022d7f94170.
- Holly Kordasiewicz: Executive Vice President, Chief Development Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:14. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:9289d9763172eecb33bdc233bb32eef61c15c1946190988644353c27aac34c3b.
- Joseph T. Baroldi: Executive Vice President, Chief Business Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:15. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:be01d22c377a6a0ef600b97130ac6dd50109e0472e20508934f383c4f0332e06.
- Kyle Jenne: Executive Vice President, Chief Global Product Strategy Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:16. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:38b0865b15381b1f4ab80f6a0066a7f1015642bb96d11dcda3113aadd19018ad.
- Patrick R. O Neil: Executive Vice President, Chief Legal Officer, General Counsel and Corporate Secretary. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:17. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:1c930cd5fa03c976e5b0c0859b19f6fdd5c8195dea9f2a9323a1bd932575e760.
- Shannon L. Devers: Executive Vice President, Chief Human Resources Officer. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:leadership_role:18. Valid from: 2026-04-23. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:2f2335db39a49b2fbf2f6a0193ee296cea27d8a0b3e067ecc976fb83ae572247.

## Roles

- PUBLISHED

## Governance

- NOT_ASSERTED

## Board committees

- Compensation: Chair not stated; Members Joan E. Herman; Spencer R. Berthelsen. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:committee_record:19. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e42281f3c82ba1c74895b3aadafaa8e662e74170a01e38703d41bec8afac6586.

## Financials

- NOT_ASSERTED

## Workforce

- NOT_ASSERTED

## Market and index context

- PUBLISHED

## Legal Name

- IONIS PHARMACEUTICALS INC. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808.

## Entity Status

- Public listing published. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808.

## Published Fact

- US. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808.
- Healthcare. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:published_fact:5. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808.

## Committee Appointment

- Joan E. Herman: member, Compensation. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:committee_appointment:20. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e42281f3c82ba1c74895b3aadafaa8e662e74170a01e38703d41bec8afac6586.
- Spencer R. Berthelsen: member, Compensation. Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:committee_appointment:21. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:e42281f3c82ba1c74895b3aadafaa8e662e74170a01e38703d41bec8afac6586.

## Security Listing

- IONS (NASDAQ). Claim: alpha:claim:company:5124c2a9-ab11-4eb4-ab35-3f7ee52af0e9:security_listing:22. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808.

## Coverage states

| Field | Value |
| --- | --- |
| Identity | PUBLISHED |
| Business | PUBLISHED |
| Leadership | PUBLISHED |
| Board and committees | PUBLISHED |
| Governance | NOT_ASSERTED |
| Financials | NOT_ASSERTED |
| Workforce | NOT_ASSERTED |
| Ownership | NOT_ASSERTED |
| Ratings | NOT_PUBLISHED |
| Market and index context | PUBLISHED |

## Public sources

- alpha:projection-evidence:14595143841161a6dea932206e8fa943ff5e03fecb5872f2be6e1ae78e91a808: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc).
- alpha:projection-evidence:document:9b9f6a7411d44c1aa4fa09093d959ebf1b50fbb64c23ffb89a526dc9dfb08464: [Ionis Pharmaceuticals DEF 14A 2026-04-23](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:49a71ce8bbffb84853586868d47cbc3e77adc02650d82db945180c0d50dcab42: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:8878d4a5960ec580beffcc484bd84c83ce1c926f639f742368035874ac238f39: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:47e558adea11e378b979447f63aec41c7199f29a4065b8ebc0df83acc7255c81: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:dcb41d0451de496b35df284812771020df8fe78f5360bf95635657d4b916d6b2: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:3ebb466a25fae76f35f4bd8f50c25f90a075b15dd38861ab88788b8cb638897c: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:d1fc57a8f0c33dd4ca416b305f1ffce040f3cec171ad77044fe14022d7f94170: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:9289d9763172eecb33bdc233bb32eef61c15c1946190988644353c27aac34c3b: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:be01d22c377a6a0ef600b97130ac6dd50109e0472e20508934f383c4f0332e06: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:38b0865b15381b1f4ab80f6a0066a7f1015642bb96d11dcda3113aadd19018ad: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:1c930cd5fa03c976e5b0c0859b19f6fdd5c8195dea9f2a9323a1bd932575e760: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:document:2f2335db39a49b2fbf2f6a0193ee296cea27d8a0b3e067ecc976fb83ae572247: [IONS DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).
- alpha:projection-evidence:e42281f3c82ba1c74895b3aadafaa8e662e74170a01e38703d41bec8afac6586: [Compensation](https://www.sec.gov/Archives/edgar/data/874015/000114036126016388/ny20063671x1_def14a.htm).

## Rights

| Field | Value |
| --- | --- |
| public_retrieval | allowed |
| agent_retrieval | allowed |
| redistribution | not_granted |
| model_training | not_granted |
| commercial_use | not_specified |
| relationship_pathfinding | not_granted |
| direct_contact | not_granted |

## Limitations

- Absence of a leadership role, committee, or disclosure is not evidence that it does not exist.
- Only explicitly published canonical company identity and current confirmed public roles are included.
- Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist.
- Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights.
- This Company Profile is an identity and evidence record, not an Alpha rating.

## Alternate representations

- [Canonical profile](https://registry.alpha.ac/companies/ionis-pharmaceuticals-inc)
- [Public Markdown](https://registry.alpha.ac/companies/ionis-pharmaceuticals-inc.md)
- [Public JSON](https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=record)
- [JSON-LD](https://registry.alpha.ac/api/public/companies/ionis-pharmaceuticals-inc?format=jsonld)
- MCP resource: `alpha://companies/ionis-pharmaceuticals-inc` at https://mcp.alpha.ac/mcp


## Connected governance records

Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage.

## Critical-risk oversight

Snapshot as of 2026-10-17T09:44:42.150816+00:00; recorded 2026-10-17T09:44:42.150816+00:00. Every published assignment for this snapshot is listed.
Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording.
An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.